SCHEMBL30559643

SCHEMBL30559643

O=C(O)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ncn2)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMO O15229 5/20 0.56
LOXL2 Q9Y4K0 1/20 0.56
TP53 P04637 2/20 0.50
TSHR P16473 1/20 0.50
RAB9A P51151 3/20 0.49
KDM4E B2RXH2 3/20 0.49
NPC1 O15118 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 2/20 0.49
LDHA P00338 1/20 0.48
RXRA P19793 2/20 0.47
RXRB P28702 2/20 0.47
BCL2L1 Q07817 1/20 0.47
BAD Q92934 1/20 0.47
P4HA1 P13674 1/20 0.47
P4HTM Q9NXG6 1/20 0.47
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16380507 0.87 LOXL2 (0.49) KMOLOXL2TP53RAB9AKDM4E
SCHEMBL4900073 0.84 KMO (0.69) KMOTSHRKDM4EALDH1A1LDHA
SCHEMBL2633158 0.83 LOXL2 (0.46) KMOLOXL2TP53RAB9AKDM4E
SCHEMBL28001472 0.82 KMO (0.54) KMOSMN1; SMN2RXRARXRBGAA
SCHEMBL4772421 0.79 CAMK2D (0.54) LOXL2TP53TSHRRAB9AKDM4E
SCHEMBL824386 0.77 LDHA (0.60) LOXL2TP53TSHRRAB9AKDM4E
SCHEMBL31388676 0.77 CTRC (0.66) LOXL2TP53TSHRRAB9AKDM4E
SCHEMBL20074743 0.76 LOXL2 (0.60) KMOLOXL2RAB9AKDM4ENPC1
SCHEMBL29129885 0.76 TP53 (0.57) LOXL2TP53TSHRRAB9AKDM4E
SCHEMBL31658242 0.75 CTRC (0.59) KDM4EALDH1A1RXRARXRBBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116804088-A Preparation method of aluminum-based MOF material with high trace benzene adsorption 浙江大学 2023-09-26 CN claimed
CN-116535662-A H-based 2 preparation method of Zr-MOF material constructed by pmbda 长春工业大学 2023-08-04 CN claimed
CN-116804088-A Preparation method of aluminum-based MOF material with high trace benzene adsorption 浙江大学 2023-09-26 CN disclosed
CN-116535662-A H-based 2 preparation method of Zr-MOF material constructed by pmbda 长春工业大学 2023-08-04 CN disclosed
CN-116535662-A H-based 2 preparation method of Zr-MOF material constructed by pmbda 长春工业大学 2023-08-04 CN disclosed