Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | CDK9 | P50750 | 6/20 | 0.43 |
| ▸ | RAF1 | P04049 | 3/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | WNT1 | P04628 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576247 | 0.84 | DYRK1A (0.47) | CDK9RAF1WNT1DYRK1ABRAF | |
| SCHEMBL30576045 | 0.80 | RXRA (0.46) | MAPK14RAF1HSPB1LYNPTGER4 | |
| SCHEMBL30576040 | 0.77 | PROKR1 (0.48) | MAPK14RAF1HSPB1LYNGSK3B | |
| SCHEMBL30576058 | 0.76 | RXRA (0.46) | MAPK14IRAK4RXRAGSK3B | |
| SCHEMBL30576121 | 0.71 | MAPK14 (0.52) | MAPK14WNT1DYRK1ARXRAGSK3B | |
| SCHEMBL30576180 | 0.71 | POLB (0.47) | MAPK14WNT1DYRK1ARXRAGSK3B | |
| SCHEMBL30576107 | 0.70 | RAB9A (0.54) | MAPK14DYRK1AGSK3B | |
| SCHEMBL30576125 | 0.69 | GSK3A (0.45) | MAPK14WNT1DYRK1AGSK3B | |
| SCHEMBL29083757 | 0.69 | RXRA (0.60) | MAPK14DYRK1ARXRAGSK3B | |
| SCHEMBL29083767 | 0.69 | RXRA (0.58) | MAPK14DYRK1ARXRAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |