Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SI | P14410 | 2/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320682 | 0.86 | ALDH1A1 (0.45) | KMT2ACYP2C19ALDH1A1HSD17B10LMNA | |
| SCHEMBL17231843 | 0.84 | LMNA (0.40) | CA1CA2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL9443410 | 0.81 | MAPK1 (0.37) | CA1CA2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL632730 | 0.81 | CYP2C19 (0.36) | KMT2ACYP2C19ALDH1A1HSD17B10LMNA | |
| SCHEMBL9790004 | 0.81 | SOAT1 (0.50) | KMT2ACYP2C19ALDH1A1HSD17B10LMNA | |
| SCHEMBL17050361 | 0.80 | CA1 (0.33) | CA1CA2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL15085753 | 0.80 | HTT (0.38) | CA1CA2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL13909023 | 0.78 | KMT2A (0.34) | KMT2ACYP2C19 | |
| SCHEMBL29310395 | 0.78 | KMT2A (0.34) | KMT2ACYP2C19 | |
| SCHEMBL14351453 | 0.78 | DGAT1 (0.37) | CA1CA2SMN1; SMN2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687490-B2 | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2010-03-30 | — | — | US | claimed |
| EP-1870412-A1 | 2-THIOETHENYL CARBAPENEM DERIVATIVE | MEIJI SEIKA KAISHA LTD. (JP) | 2007-12-26 | — | — | EP | claimed |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-01-04 | — | — | US | claimed |
| EP-1083247-B9 | Use of organic carbonates as solvents for the washing of metal surfaces | POLIMERI EUROPA SPA (IT) | 2006-03-22 | — | — | EP | claimed |
| EP-1083247-B1 | Use of organic carbonates as solvents for the washing of metal surfaces | POLIMERI EUROPA SPA (IT) | 2005-11-16 | — | — | EP | claimed |
| US-6818049-B1 | HALOGEN FREE INDUSTRIAL SOLVENT FORMULATION; LOW REACTIVITY TO OZONE FORMATION | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-11-16 | — | — | US | claimed |
| US-6506243-B1 | Industrial solvents; dialkyl carbonates, alkyl acetates, dioxolanes, pivalates, isobutyrates, nitriles | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-01-14 | — | — | US | claimed |
| WO-2002064687-A1 | ENVIRONMENTALLY PREFERRED FLUIDS AND FLUID BLENDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-08-22 | — | — | WO | claimed |
| EP-1090085-A1 | ENVIRONMENTALLY PREFERRED FLUIDS AND FLUID BLENDS | EXXON CHEMICAL PATENTS INC. (US) | 2001-04-11 | — | — | EP | claimed |
| WO-1999057217-A1 | ENVIRONMENTALLY PREFERRED FLUIDS AND FLUID BLENDS | EXXON CHEMICAL PATENTS INC. (US) | 1999-11-11 | — | — | WO | claimed |
| US-5659062-A | CARBONATE COMPOUNDS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-19 | — | — | US | claimed |
| CN-118900839-A | Antiviral compounds and methods of making and using the same | 吉利德科学公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-113164506-B | Dinucleotide compounds and prodrugs thereof | 正大天晴药业集团股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| US-20230322793-A1 | 10-(di(phenyl)methyl)-4-hydroxy-8,9,9A,10-tetrahydro-7H-pyrrolo[1 ',2':4,5]pyrazino[1,2-B]pyridazine-3,5-dione Derivatives and Related Compounds as Inhibitors of the Orthomyxovirus Replication for Treating Influenza | NOVARTIS AG (CH) | 2023-10-12 | — | — | US | disclosed |
| CN-116437930-A | Use of uridine derivatives in the preparation of medicaments | 上海岸阔医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| US-5633099-A | Carbonate compounds, non-aqueous electrolytic solutions and batteries comprising non-aqueous electrolytic solutions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0599534-B1 | Novel carbonate compounds, non-aqueous electrolytic solutions and batteries comprising nonaqueous electrolytic solutions | MITSUI PETROCHEMICAL IND (JP) | 1997-04-16 | — | — | EP | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |
| EP-0599534-A1 | Novel carbonate compounds, non-aqueous electrolytic solutions and batteries comprising nonaqueous electrolytic solutions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MTAP, BLVRB, BPGM | KMT2A 351/4885CA1 3160/4885CA2 1641/4885 |
| US-20230322793-A1 | 10-(di(phenyl)methyl)-4-hydroxy-8,9,9A,10-tetrahydro-7H-pyrrolo[1 ',2':4,5]pyrazino[1,2-B]pyridazine-3,5-dione Derivatives and Related Compounds as Inhibitors of the Orthomyxovirus Replication for Treating Influenza | MAVS, ZC3HAV1, EIF2AK2 | KMT2A 1290/4885CA1 4814/4885CA2 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.