Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056414 | 0.90 | MEN1 (0.48) | FAAHMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL3061812 | 0.89 | HIF1A (0.53) | LOXL2FAAHPRKAA2RAB9A | |
| SCHEMBL3067957 | 0.85 | KCNQ3 (0.47) | KCNQ3KCNQ2KCNE1KCNQ1MAPT | |
| SCHEMBL10181012 | 0.84 | LOXL2 (0.38) | LOXL2KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL3045763 | 0.81 | KCNQ3 (0.44) | KCNQ3KCNQ2KCNE1KCNQ1MAPT | |
| SCHEMBL3035668 | 0.79 | PRKAA2 (0.58) | FAAHPRKAA2KDM4EALDH1A1LMNA | |
| SCHEMBL3059769 | 0.79 | LMNA (0.46) | LOXL2FAAHMAPTKDM4EALDH1A1 | |
| SCHEMBL3031846 | 0.75 | MAPT (0.48) | FAAHPRKAA2MAPTKDM4ERAB9A | |
| SCHEMBL3060416 | 0.74 | MEN1 (0.49) | FAAHMAPTALDH1A1RAB9ALMNA | |
| SCHEMBL13742301 | 0.74 | KDM4E (0.47) | MAPTKDM4ERAB9APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551999-B2 | Heterocyclic compound and pharmaceutical composition thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | disclosed |
| US-20100261720-A1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261720-A1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | COL1A1, COL2A1, COL14A1 | LOXL2 2070/4885FAAH 2709/4885PRKAA2 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.