SCHEMBL30584749

SCHEMBL30584749

CC(=O)Nc1ccc(-c2noc(N3CCC(C(=O)NCC4CCN(Cc5ccc(C)cc5)C4)CC3)n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.53
▸ TP53 P04637 3/20 0.52
▸ MAPT P10636 3/20 0.51
▸ CCR5 P51681 1/20 0.51
▸ RXFP3 Q9NSD7 2/20 0.47
▸ SIRT2 Q8IXJ6 1/20 0.46
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ USP2 O75604 1/20 0.45
▸ TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25433137 0.91 CCR5 (0.53) LMNATP53MAPTCCR5MEN1
Formic Acid SCHEMBL30585045 0.89 CCR5 (0.48) LMNATP53MAPTCCR5MEN1
SCHEMBL25437981 0.88 LMNA (0.59) LMNAMAPTCCR5MEN1KMT2A
SCHEMBL30584823 0.88 ACHE (0.51) LMNATP53MAPTCCR5MEN1
SCHEMBL30584949 0.86 MEN1 (0.49) LMNAMAPTCCR5MEN1KMT2A
SCHEMBL31546362 0.86 CCR5 (0.54) LMNATP53MAPTCCR5MEN1
SCHEMBL30584795 0.85 CCR5 (0.52) LMNATP53MAPTCCR5MEN1
SCHEMBL25434022 0.85 CCR5 (0.52) LMNATP53MAPTCCR5MEN1
SCHEMBL30584714 0.84 CCR5 (0.48) LMNAMAPTCCR5MEN1KMT2A
SCHEMBL25439449 0.84 CCR5 (0.49) LMNAMAPTCCR5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 LMNA 1344/4885TP53 54/4885MAPT 2999/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 LMNA 1344/4885TP53 54/4885MAPT 2999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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