SCHEMBL30584949

SCHEMBL30584949

Cc1ccc(CN2CCC(CNC(=O)C3CCN(c4nc(-c5ccc(OCCO)cc5)no4)CC3)C2)cc1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.49
▸ KMT2A Q03164 4/20 0.49
▸ LMNA P02545 2/20 0.49
▸ CCR5 P51681 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ S1PR1 P21453 1/20 0.46
▸ MAPT P10636 2/20 0.45
▸ USP2 O75604 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ HRH3 Q9Y5N1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25437981 0.92 LMNA (0.59) MEN1KMT2ALMNACCR5SMN1; SMN2
SCHEMBL25435838 0.91 MEN1 (0.47) MEN1KMT2ALMNACCR5SMN1; SMN2
SCHEMBL30584714 0.91 CCR5 (0.48) MEN1KMT2ALMNACCR5SMN1; SMN2
SCHEMBL25402462 0.90 LMNA (0.46) MEN1KMT2ALMNASMN1; SMN2S1PR1
SCHEMBL30584748 0.90 LMNA (0.46) MEN1KMT2ALMNASMN1; SMN2S1PR1
SCHEMBL25433137 0.89 CCR5 (0.53) MEN1KMT2ALMNACCR5SMN1; SMN2
SCHEMBL30584823 0.88 ACHE (0.51) MEN1KMT2ALMNACCR5MAPT
Formic Acid SCHEMBL31546458 0.86 CHRM4 (0.50) MEN1KMT2ALMNACCR5
Formic Acid SCHEMBL25433004 0.86 MEN1 (0.47) MEN1KMT2ALMNACCR5SMN1; SMN2
SCHEMBL30584749 0.86 LMNA (0.53) MEN1KMT2ALMNACCR5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885LMNA 1344/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885LMNA 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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