SCHEMBL25435838

SCHEMBL25435838

Cc1ccc(CN2CCC(CNC(=O)C3CCN(c4nc(-c5ccc(OCC(O)CO)cc5)no4)CC3)C2)cc1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.47
▸ KMT2A Q03164 4/20 0.47
▸ CCR5 P51681 1/20 0.47
▸ LMNA P02545 3/20 0.47
▸ MAPT P10636 3/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ USP2 O75604 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25401425 0.91 LMNA (0.43) MEN1KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL30584949 0.91 MEN1 (0.49) MEN1KMT2ACCR5LMNAMAPT
SCHEMBL25437981 0.88 LMNA (0.59) MEN1KMT2ACCR5LMNAMAPT
SCHEMBL30584714 0.87 CCR5 (0.48) MEN1KMT2ACCR5LMNAMAPT
SCHEMBL25433137 0.86 CCR5 (0.53) MEN1KMT2ACCR5LMNAMAPT
SCHEMBL30584823 0.85 ACHE (0.51) MEN1KMT2ACCR5LMNAMAPT
Formic Acid SCHEMBL25433004 0.85 MEN1 (0.47) MEN1KMT2ACCR5LMNAMAPT
Formic Acid SCHEMBL31546458 0.83 CHRM4 (0.50) MEN1KMT2ACCR5LMNA
SCHEMBL30584749 0.83 LMNA (0.53) MEN1KMT2ACCR5LMNAMAPT
SCHEMBL30584743 0.83 CCR5 (0.51) MEN1KMT2ACCR5LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885CCR5 3713/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885CCR5 3713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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