Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30585267 | 0.89 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL30585254 | 0.84 | BCHE (0.49) | L3MBTL1ALDH1A1KDM4EPOLBSIGMAR1 | |
| SCHEMBL29078428 | 0.82 | CYP1A2 (0.57) | L3MBTL1CYP1A2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL30585257 | 0.82 | CYP1A2 (0.57) | L3MBTL1CYP1A2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL30585250 | 0.81 | LMNA (0.54) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30205256 | 0.81 | MYD88 (0.62) | L3MBTL1CYP3A4ALDH1A1TDP1MEN1 | |
| SCHEMBL28954884 | 0.81 | MYD88 (0.62) | L3MBTL1CYP3A4ALDH1A1TDP1MEN1 | |
| SCHEMBL30585263 | 0.78 | SIGMAR1 (0.50) | MEN1KMT2ASMN1; SMN2LMNASIGMAR1 | |
| SCHEMBL29078366 | 0.78 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL30585265 | 0.78 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | claimed |
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | disclosed |