Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30585254 | 0.88 | BCHE (0.49) | SIGMAR1ACHEHTR1AHTR7 | |
| SCHEMBL30585267 | 0.82 | L3MBTL1 (0.52) | SMN1; SMN2FAAHACHEKMT2ALMNA | |
| SCHEMBL29078387 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2FAAHACHEMEN1KMT2A | |
| SCHEMBL30585245 | 0.78 | L3MBTL1 (0.56) | SIGMAR1SMN1; SMN2FAAHACHEMEN1 | |
| SCHEMBL29078397 | 0.78 | ALDH1A1 (0.53) | HTR1A | |
| SCHEMBL26101473 | 0.75 | RAB9A (0.58) | SMN1; SMN2FAAHKMT2AMMP1MMP2 | |
| SCHEMBL29078375 | 0.75 | CHKA (0.50) | SIGMAR1SMN1; SMN2FAAHACHEHTR7 | |
| SCHEMBL30585266 | 0.75 | CHKA (0.50) | SIGMAR1SMN1; SMN2FAAHACHEHTR7 | |
| SCHEMBL30585253 | 0.73 | TSHR (0.47) | SIGMAR1SMN1; SMN2FAAHACHEKMT2A | |
| SCHEMBL29078393 | 0.73 | ACHE (0.53) | SIGMAR1FAAHACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | claimed |
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | disclosed |