Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799199 | 0.89 | MAOA (0.37) | THRBMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL3982720 | 0.89 | MAOA (0.37) | THRBMAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL2298637 | 0.76 | CASP1 (0.37) | CASP1CASP7HSD17B10THRBMAPT | |
| SCHEMBL14346731 | 0.76 | HSD17B10 (0.37) | CASP1CASP7HSD17B10THRBMAPT | |
| SCHEMBL17605997 | 0.76 | PBRM1 (0.33) | KDM4EPBRM1L3MBTL1TDP1 | |
| SCHEMBL2298063 | 0.76 | PBRM1 (0.41) | CASP1CASP7HSD17B10THRBMAPT | |
| SCHEMBL18854464 | 0.76 | TYMS (0.42) | MAPTKDM4EALDH1A1GAAHPGD | |
| Bromide SCHEMBL2296695 | 0.74 | PBRM1 (0.40) | CASP1CASP7HSD17B10THRBMAPT | |
| SCHEMBL3982261 | 0.73 | CES1 (0.31) | — | |
| SCHEMBL24575396 | 0.72 | KDM4E (0.56) | HSD17B10MAPTLMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10807997-B2 | Methods for making quinolinyldiamines | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-10807997-B2 | Methods for making quinolinyldiamines | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2020-10-20 | — | — | US | disclosed |
| WO-2020046794-A1 | METHODS FOR MAKING QUINOLINYLDIAMINES | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2020-03-05 | — | — | WO | disclosed |
| US-20200071344-A1 | METHODS FOR MAKING QUINOLINYLDIAMINES | EXXONMOBIL CHEMICAL PATENTS INC. | 2020-03-05 | — | — | US | disclosed |
| US-20200071344-A1 | METHODS FOR MAKING QUINOLINYLDIAMINES | EXXONMOBIL CHEMICAL PATENTS INC. | 2020-03-05 | — | — | US | disclosed |
| US-8399490-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399490-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399490-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100273830-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100273830-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100273830-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| EP-2167484-A2 | CONDENSED ANTHRANILAMIDE INSECTICIDES | Syngeta Participations AG (CH) | 2010-03-31 | — | — | EP | disclosed |
| US-7491718-B2 | Sulfonamides having antiangiogenic and anticancer activity | ABBOTT LABORATORIES (US) | 2009-02-17 | — | — | US | disclosed |
| WO-2009010260-A2 | CONDENSED ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-01-22 | — | — | WO | disclosed |
| EP-1549613-A1 | SULFONAMIDES HAVING ANTIANGIOGENIC AND ANTICANCER ACTIVITY | Abbott Laboratories (US) | 2005-07-06 | — | — | EP | disclosed |
| US-20040167128-A1 | Sulfonamides having antiangiogenic and anticancer activity | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040157836-A1 | Sulfonamides having antiangiogenic and anticancer activity | ABBOTT LABORATORIES | 2004-08-12 | — | — | US | disclosed |
| WO-2004033419-A1 | SULFONAMIDES HAVING ANTIANGIOGENIC AND ANTICANCER ACTIVITY | ABBOTT LABORATORIES (US) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167128-A1 | Sulfonamides having antiangiogenic and anticancer activity | METAP2, METAP1, DNPEP | CASP1 1675/4885CASP7 1198/4885HSD17B10 3758/4885 |
| US-20100273830-A1 | NOVEL INSECTICIDES | NR5A2, NR2C2, NOX5 | CASP1 1424/4885CASP7 872/4885HSD17B10 1555/4885 |
| US-20200071344-A1 | METHODS FOR MAKING QUINOLINYLDIAMINES | NNMT, PNMT, HNMT | CASP1 4117/4885CASP7 1804/4885HSD17B10 1501/4885 |
| US-10807997-B2 | Methods for making quinolinyldiamines | NNMT, PNMT, HNMT | CASP1 4117/4885CASP7 1804/4885HSD17B10 1501/4885 |
| US-20040157836-A1 | Sulfonamides having antiangiogenic and anticancer activity | METAP2, METAP1, DNPEP | CASP1 1675/4885CASP7 1198/4885HSD17B10 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.