Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30234297 | 0.76 | SIRT2 (0.37) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL30602664 | 0.76 | SIRT2 (0.37) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL20828305 | 0.76 | SIRT2 (0.37) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL20828310 | 0.70 | ALDH1A1 (0.40) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30602672 | 0.70 | ALDH1A1 (0.40) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL20828403 | 0.69 | DGAT1 (0.41) | RAB9ASMN1; SMN2LMNANPC1MAPT | |
| SCHEMBL20828406 | 0.69 | SLC6A5 (0.44) | KMT2AMCHR1 | |
| SCHEMBL20832880 | 0.66 | MAPT (0.46) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL22227987 | 0.66 | VCP (0.41) | NPC1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL20828522 | 0.66 | RAB9A (0.43) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |