Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 4/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459253 | 1.00 | ALDH1A1 (0.77) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL7270563 | 1.00 | ALDH1A1 (0.77) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL29459410 | 1.00 | ALDH1A1 (0.77) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL28661085 | 1.00 | ALDH1A1 (0.77) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL4861809 | 0.87 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL392680 | 0.87 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL30216480 | 0.87 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL478614 | 0.87 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL30632385 | 0.86 | AADAT (0.60) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| Hydrochloric Acid SCHEMBL7840775 | 0.85 | ALDH1A1 (0.97) | ALDH1A1GAAPOLBL3MBTL1AADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778827-B1 | PROCESS FOR PRODUCING A BETA-AMINO ALCOHOL | DEGUSSA (DE) | 2001-12-12 | — | — | EP | claimed |
| US-5994555-A | (4S,5S)-4-BENZYL-2-OXO-OXAZOLIDINE-5-CARBOXYLIC ACID FROM PHENYLALANINE AND PHTHALIC ANHYDRIDE | F. HOFFMAN-LAROCHE AG (CH) | 1999-11-30 | — | — | US | claimed |
| US-5859248-A | Process for the production of a β-amino alcohol | F. HOFFMAN-LA ROCHE AG (CH) | 1999-01-12 | — | — | US | claimed |
| US-5321166-A | Method for the production of aldehydes | HOFFMANN-LA ROCHE INC. (US) | 1994-06-14 | — | — | US | claimed |
| EP-3924349-A2 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | The Roskamp Institute (US) | 2021-12-22 | — | — | EP | disclosed |
| CN-113614074-A | Amino acid derivatives for the treatment of inflammatory diseases | 罗斯坎普研究所 | 2021-11-05 | — | — | CN | disclosed |
| WO-2020053373-A1 | NOVEL TRF1 MODULATORS AND ANALOGUES THEREOF | Fundación Del Sector Público Estatal Centro Nacional De Investigaciones Oncológicas Carlos III (F.S.P. CNIO) (ES) | 2020-03-19 | — | — | WO | disclosed |
| WO-2013006792-A1 | ANTIVIRAL COMPOUNDS | PHARMARESOURCES (SHANGHAI) CO., LTD. (CN) | 2013-01-10 | — | — | WO | disclosed |
| US-5994555-A | (4S,5S)-4-BENZYL-2-OXO-OXAZOLIDINE-5-CARBOXYLIC ACID FROM PHENYLALANINE AND PHTHALIC ANHYDRIDE | F. HOFFMAN-LAROCHE AG (CH) | 1999-11-30 | — | — | US | disclosed |
| US-5919949-A | α-hydroxy acid esters useful as intermediates in the production of β-amino alcohols | HOFFMANN-LA ROCHE INC. (US) | 1999-07-06 | — | — | US | disclosed |
| US-5859248-A | Process for the production of a β-amino alcohol | F. HOFFMAN-LA ROCHE AG (CH) | 1999-01-12 | — | — | US | disclosed |
| US-5698698-A | Process for preparation of N-tert.butyl-decahydro-2- 2(R)-hydroxy-4-phenyl-3(S)-phthalimidobutyl!-(4aS,8aS)-isoquinoline-3(S)-carboxamide | HOFFMANN-LA ROCHE INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5495025-A | Isoindole compounds which are useful as intermediates | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5488115-A | Alcohols | HOFFMANN-LA ROCHE INC. (US) | 1996-01-30 | — | — | US | disclosed |
| US-5455353-A | 4-(benzyl-2-oxo-oxazolidin-5 ylmethyl)N tertbutyl-decahydroisoquinoline-3-carboxamides | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5451678-A | Intermediates for viricides | HOFFMANN-LA ROCHE INC. (US) | 1995-09-19 | — | — | US | disclosed |
| CN-1104641-A | Process for preparing N-tert-butylamides | HOFFMANN LA ROCHE (CH) | 1995-07-05 | — | — | CN | disclosed |
| US-5321166-A | Method for the production of aldehydes | HOFFMANN-LA ROCHE INC. (US) | 1994-06-14 | — | — | US | disclosed |
| US-4147700-A | HYDRAZINOLYZING A PHTHALYL DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4141901-A | REDUCING AN AZIDO DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1979-02-27 | — | — | US | disclosed |