Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 4/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840770 | 1.00 | ALDH1A1 (0.77) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL7270563 | 1.00 | ALDH1A1 (0.77) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL29459410 | 1.00 | ALDH1A1 (0.77) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL28661085 | 1.00 | ALDH1A1 (0.77) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL4861809 | 0.87 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL392680 | 0.87 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL30216480 | 0.87 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL478614 | 0.87 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| SCHEMBL30632385 | 0.86 | AADAT (0.60) | ALDH1A1GAAPOLBL3MBTL1AADAT | |
| Hydrochloric Acid SCHEMBL7840775 | 0.85 | ALDH1A1 (0.97) | ALDH1A1GAAPOLBL3MBTL1AADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924349-B1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | THE ROSKAMP INST (US) | 2025-06-25 | — | — | EP | disclosed |
| CN-117024327-A | Isoindolinone-based derivative, and preparation method and application thereof | 华东理工大学 | 2023-11-10 | — | — | CN | disclosed |
| US-20220081415-A1 | Amino Acid Derivatives for the Treatment of Inflammatory Diseases | THE ROSKAMP INST (US) | 2022-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220081415-A1 | Amino Acid Derivatives for the Treatment of Inflammatory Diseases | NFKBIA, NFRKB, IKBKG | ALDH1A1 4214/4885GAA 828/4885POLB 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.