Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.61 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | KYNU | Q16719 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10872062 | 0.99 | SIRT2 (0.60) | SIRT2SIRT1SIRT3CA1CA2 | |
| SCHEMBL27892488 | 0.96 | SIRT2 (0.57) | SIRT2SIRT1SIRT3CA1CA2 | |
| SCHEMBL9500591 | 0.93 | SIRT2 (0.54) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL631840 | 0.91 | FOLH1 (0.59) | SIRT2SIRT1CTSLCTSSSIRT5 | |
| SCHEMBL6768020 | 0.91 | FOLH1 (0.59) | SIRT2SIRT1CTSLCTSSSIRT5 | |
| SCHEMBL5145708 | 0.91 | FOLH1 (0.59) | SIRT2SIRT1CTSLCTSSSIRT5 | |
| Hydrochloric Acid SCHEMBL29401494 | 0.90 | FOLH1 (0.58) | SIRT2SIRT1CTSLCTSSSIRT5 | |
| Hydrochloric Acid SCHEMBL333888 | 0.90 | FOLH1 (0.58) | SIRT2SIRT1CTSLCTSSSIRT5 | |
| Water SCHEMBL7274005 | 0.90 | FOLH1 (0.58) | SIRT2SIRT1CTSLCTSSSIRT5 | |
| Hydrochloric Acid SCHEMBL333889 | 0.90 | FOLH1 (0.58) | SIRT2SIRT1CTSLCTSSSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222549-A1 | DECHALCOGENATIVE METHODS FOR THE PREPARATION OF ALLYLIC SULFIDES | NIH-DEITR | 2010-09-02 | — | — | US | disclosed |
| EP-2139859-A1 | DECHALCOGENATIVE METHODS FOR THE PREPARATION OF ALLYLIC SULFIDES | The Board Of Trustees Of The University Of Illinois (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008134058-A1 | DECHALCOGENATIVE METHODS FOR THE PREPARATION OF ALLYLIC SULFIDES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222549-A1 | DECHALCOGENATIVE METHODS FOR THE PREPARATION OF ALLYLIC SULFIDES | TST, SCLY, AP2S1 | SIRT2 1925/4885SIRT1 3205/4885SIRT3 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.