Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643651 | 1.00 | YAP1 (0.38) | YAP1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL26641237 | 0.91 | PRMT5 (0.39) | YAP1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL30643684 | 0.84 | OPRD1 (0.42) | YAP1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL30643626 | 0.84 | TLR9 (0.36) | YAP1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL26641508 | 0.82 | OPRD1 (0.41) | YAP1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL30830759 | 0.81 | HSD17B10 (0.40) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL26641379 | 0.81 | PRMT5 (0.40) | YAP1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL26641553 | 0.79 | OPRD1 (0.42) | YAP1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL30831067 | 0.79 | HSD17B10 (0.51) | USP30SCD5GPR119 | |
| SCHEMBL30965537 | 0.79 | SCD5 (0.44) | USP30SCD5GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |