SCHEMBL3064572

SCHEMBL3064572

CC(C)OP(=O)(COC1(COC(c2ccccc2)(c2ccccc2)c2ccccc2)CC1)OC(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KIF11 P52732 1/20 0.32
KDM4E B2RXH2 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14244434 0.74 ALDH1A1 (0.38) ALDH1A1L3MBTL1KIF11KDM4ETDP1
SCHEMBL12999105 0.70 KDM4E (0.32) ALDH1A1KDM4E
SCHEMBL3146365 0.69
SCHEMBL12999093 0.69 KDM4E (0.31) ALDH1A1KDM4E
SCHEMBL8383114 0.65 KIF11 (0.44) ALDH1A1L3MBTL1KIF11
SCHEMBL188157 0.65 KIF11 (0.42) KIF11
SCHEMBL2912398 0.63 CTSA (0.33) ALDH1A1KDM4E
SCHEMBL1375594 0.62 L3MBTL1 (0.43) ALDH1A1L3MBTL1KDM4ETDP1
SCHEMBL14260068 0.62 KCNN4 (0.39) ALDH1A1L3MBTL1KIF11KDM4ETDP1
SCHEMBL3288254 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7795463-B2 Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate LG LIFE SCIENCES LTD. (KR) 2010-09-14 US claimed
US-20090187019-A1 Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate LG LIFE SCIENCE LTD. (KR) 2009-07-23 US claimed
US-20100305364-A1 PROCESS FOR PREPARING DIISOPROPYL((1-(HYDROXYMETHYL)-CYCLOPROPYL)OXY)METHYLPHOSPHONATE YOON SUK-KYOON 2010-12-02 US disclosed
US-7795463-B2 Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate LG LIFE SCIENCES LTD. (KR) 2010-09-14 US disclosed
US-7795463-B2 Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate LG LIFE SCIENCES LTD. (KR) 2010-09-14 US disclosed
US-20090187019-A1 Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate LG LIFE SCIENCE LTD. (KR) 2009-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305364-A1 PROCESS FOR PREPARING DIISOPROPYL((1-(HYDROXYMETHYL)-CYCLOPROPYL)OXY)METHYLPHOSPHONATE DHPS, ITPA, DCPS ALDH1A1 2572/4885L3MBTL1 3021/4885KIF11 3491/4885
US-20090187019-A1 Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate DHPS, ITPA, DCPS ALDH1A1 2572/4885L3MBTL1 3021/4885KIF11 3491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.