SCHEMBL30656100

SCHEMBL30656100

Cc1sc2ccc(OCc3ccccc3F)cc2c1C(=O)N[C@@H]1CCN(CCO)C1=O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SCN3A Q9NY46 4/20 0.38
MET P08581 2/20 0.38
KCNH2 Q12809 4/20 0.37
PARP15 Q460N3 2/20 0.37
PARP10 Q53GL7 2/20 0.37
RIPK1 Q13546 3/20 0.37
MCHR1 Q99705 1/20 0.36
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656040 1.00 SCN3A (0.38) SCN3AMETKCNH2PARP15PARP10
SCHEMBL29713018 0.85 SLC26A4 (0.47) SCN3AMETRIPK1
SCHEMBL24471024 0.85 SLC26A4 (0.47) SCN3AMETRIPK1
SCHEMBL30656139 0.83 ESR1 (0.34)
SCHEMBL30656106 0.83 ESR1 (0.34)
SCHEMBL30656145 0.82 APOL1 (0.42) SCN3AKCNH2PARP15PARP10MAOB
SCHEMBL30719746 0.76 RIPK1 (0.39) METRIPK1MCHR1
SCHEMBL30656149 0.75 PARP15 (0.41) SCN3AKCNH2PARP15PARP10MAOB
SCHEMBL26661096 0.75 KCNH2 (0.38) SCN3AKCNH2PARP15PARP10MAOB
SCHEMBL31351337 0.75 PARP10 (0.48) SCN3APARP15PARP10MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346569-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2025-11-13 US claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
US-20250346569-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2025-11-13 US disclosed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346569-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS TRPM4, TRPM2, TRPM6 SCN3A 18/4885MET 3558/4885KCNH2 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.