Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL738580 | 0.81 | ALDH1A1 (0.42) | MAPTALDH1A1GAAHPGDALOX15 | |
| SCHEMBL30666619 | 0.80 | MGLL (0.42) | ALDH1A1TSHRMRGPRX4 | |
| SCHEMBL630440 | 0.76 | MAPT (0.48) | MAPTALDH1A1GAAALOX15TSHR | |
| SCHEMBL30448711 | 0.76 | MAPT (0.42) | MAPTALDH1A1GAAALOX15TSHR | |
| Boric Acid SCHEMBL14874619 | 0.71 | GRIN2B (0.45) | MAPTHTTEPHX2RAB9AKIF11 | |
| SCHEMBL30760633 | 0.70 | ENPP2 (0.40) | TSHR | |
| SCHEMBL30359110 | 0.69 | PIM1 (0.40) | MAPTALDH1A1GAAHPGDNPC1 | |
| SCHEMBL29272668 | 0.68 | CA1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL3147185 | 0.68 | GPR3 (0.50) | CETPEPHX2KIF11 | |
| SCHEMBL6677730 | 0.68 | ENPP2 (0.41) | MAPTALDH1A1GAATSHRHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940552-A | Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2023-10-24 | — | — | CN | disclosed |