Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476969 | 0.83 | KEAP1 (0.61) | ALDH1A1KEAP1FFAR1TRPA1SMN1; SMN2 | |
| SCHEMBL14112339 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KEAP1FFAR1TRPA1SMN1; SMN2 | |
| SCHEMBL11087566 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KEAP1FFAR1TRPA1SMN1; SMN2 | |
| SCHEMBL107274 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KEAP1FFAR1SMN1; SMN2HDAC2 | |
| SCHEMBL108638 | 0.81 | CES1 (0.50) | ALDH1A1TRPA1HDAC8HDAC6KMT2A | |
| SCHEMBL691726 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KEAP1FFAR1TRPA1SMN1; SMN2 | |
| SCHEMBL28005839 | 0.80 | TRPA1 (0.54) | ALDH1A1KEAP1FFAR1TRPA1SMN1; SMN2 | |
| SCHEMBL4109558 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KEAP1FFAR1TRPA1SMN1; SMN2 | |
| SCHEMBL6512598 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KEAP1FFAR1TRPA1SMN1; SMN2 | |
| SCHEMBL12950490 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KEAP1FFAR1TRPA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563516-B | GPR156 variants and uses thereof | 雷杰纳荣制药公司 | 2023-10-27 | — | — | CN | disclosed |