SCHEMBL30673256

SCHEMBL30673256

CS(=O)(=O)S(=O)(=O)c1ccc(C=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.46
ALDH1A1 P00352 7/20 0.41
TYR P14679 1/20 0.41
CYP2A13 Q16696 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ALDH5A1 P51649 1/20 0.41
ABAT P80404 1/20 0.41
STS P08842 1/20 0.41
ALDH1A3 P47895 2/20 0.39
ALDH3A1 P30838 1/20 0.39
KDM4E B2RXH2 2/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP7 P09237 1/20 0.38
MMP9 P14780 1/20 0.38
MMP13 P45452 1/20 0.38
PTGS2 P35354 1/20 0.35
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL607349 0.81 ENPP2 (0.52) CYP2A6ALDH1A1TYRCYP2A13PTGS2
SCHEMBL13926394 0.78 CYP2A6 (0.52) CYP2A6ALDH1A1TYRCYP2A13HSD17B10
SCHEMBL22118701 0.77 CYP2A6 (0.46) CYP2A6ALDH1A1TYRCYP2A13HSD17B10
SCHEMBL9720714 0.76 MAOB (0.49) CYP2A6PTGS2
SCHEMBL4715345 0.76 PTGS2 (0.53) CYP2A6MMP1MMP2MMP3MMP7
SCHEMBL6853680 0.75 ALDH1A1 (0.48) CYP2A6ALDH1A1TYRCYP2A13HSD17B10
Benzaldehyde SCHEMBL28192263 0.74 ALDH1A1 (0.58) CYP2A6ALDH1A1PTGS2
SCHEMBL16712218 0.73 CYP2A6 (0.46) CYP2A6ALDH1A1TYRCYP2A13HSD17B10
SCHEMBL4139519 0.73 GAA (0.59) ALDH1A1KDM4EMMP1MMP2MMP9
SCHEMBL2264989 0.73 PSIP1 (0.54) CYP2A6ALDH1A1TYRCYP2A13HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4289961-A1 METHOD FOR SYNTHESIZING (1R,2R)-AMPP BY USING ENZYME CASCADE REACTION Zhejiang Apeloa Kangyu Pharmaceutical Co. Ltd. (CN) 2023-12-13 EP disclosed