Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | F13A1 | P00488 | 1/20 | 0.52 |
| ▸ | TGM1 | P22735 | 1/20 | 0.52 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808631 | 1.00 | EGFR (0.60) | EGFRTGM2KMT2AHTTLMNA | |
| SCHEMBL613090 | 0.86 | TGM2 (0.65) | EGFRTGM2LMNAF13A1TGM1 | |
| SCHEMBL31228347 | 0.86 | TGM2 (0.65) | EGFRTGM2LMNAF13A1TGM1 | |
| SCHEMBL5488606 | 0.85 | TGM2 (0.51) | EGFRTGM2KMT2AHTTLMNA | |
| SCHEMBL19279109 | 0.82 | TGM2 (0.49) | EGFRTGM2LMNAF13A1TGM1 | |
| SCHEMBL2097424 | 0.79 | KMT2A (0.60) | EGFRKMT2AHTTLMNAMEN1 | |
| SCHEMBL413017 | 0.78 | MMP1 (0.59) | TGM2KMT2AHTTLMNAMEN1 | |
| SCHEMBL9357321 | 0.78 | TGM2 (0.57) | EGFRTGM2LMNAF13A1TGM1 | |
| SCHEMBL2761954 | 0.78 | TGM2 (0.62) | EGFRTGM2KMT2ALMNAMEN1 | |
| SCHEMBL17443378 | 0.78 | TGM2 (0.57) | EGFRTGM2LMNAF13A1TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955381-A | Pyrazole compound as well as preparation method and application thereof | 赣南师范大学 | 2024-11-15 | — | — | CN | claimed |
| CN-118955381-A | Pyrazole compound as well as preparation method and application thereof | 赣南师范大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-117263760-A | Method for synthesizing tetrahydrobenzene-1-formamide compound by photocatalysis | 西南医科大学 | 2023-12-22 | — | — | CN | disclosed |