Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | GOT1 | P17174 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3406541 | 0.81 | TP53 (0.46) | GRM5L3MBTL1TP53CCR1CCR5 | |
| SCHEMBL27946276 | 0.75 | TP53 (0.37) | GRM5L3MBTL1TP53CCR1CCR5 | |
| SCHEMBL931676 | 0.74 | F7 (0.46) | GRM5L3MBTL1EGLN1HPGDSSMN1; SMN2 | |
| SCHEMBL25493617 | 0.72 | TP53 (0.38) | GRM5L3MBTL1TP53CCR1CCR5 | |
| SCHEMBL30792004 | 0.72 | GOT1 (0.46) | GRM5L3MBTL1TP53CCR1CCR5 | |
| SCHEMBL29442588 | 0.72 | GOT1 (0.46) | GRM5L3MBTL1TP53CCR1CCR5 | |
| SCHEMBL1456807 | 0.72 | GOT1 (0.46) | GRM5L3MBTL1TP53CCR1CCR5 | |
| SCHEMBL30661720 | 0.71 | L3MBTL1 (0.49) | GRM5L3MBTL1FLT3SMN1; SMN2NPC1 | |
| SCHEMBL218007 | 0.71 | L3MBTL1 (0.49) | GRM5L3MBTL1FLT3SMN1; SMN2NPC1 | |
| SCHEMBL869236 | 0.69 | GOT1 (0.39) | GRM5L3MBTL1TP53CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247395-A | PDE4B inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-12-19 | — | — | CN | disclosed |