Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30661720 | 1.00 | L3MBTL1 (0.49) | L3MBTL1EP300HDAC4DHODHGRM5 | |
| SCHEMBL13458062 | 0.80 | GABRA1 (0.52) | HDAC4DHODHRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL121970 | 0.79 | RAB9A (0.50) | HDAC4DHODHRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29959678 | 0.79 | RAB9A (0.50) | HDAC4DHODHRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6850684 | 0.78 | SLC6A2 (0.49) | L3MBTL1HDAC4DHODHRAB9ANPC1 | |
| SCHEMBL8467926 | 0.78 | HDAC4 (0.46) | HDAC4DHODHRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16780594 | 0.78 | HDAC4 (0.46) | HDAC4DHODHRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3458918 | 0.78 | NPY5R (0.47) | L3MBTL1HDAC4DHODHRAB9ANPC1 | |
| SCHEMBL8138043 | 0.78 | MAPT (0.56) | HDAC4DHODHRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30719418 | 0.78 | HDAC4 (0.46) | HDAC4DHODHRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250677-B | Polymer-based composite material containing filler particle three-dimensional network and preparation method thereof | 中国科学院深圳先进技术研究院 | 2022-10-14 | — | — | CN | claimed |
| CN-114479734-A | Insulating adhesive film, preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2022-05-13 | — | — | CN | claimed |
| US-20150168415-A1 | COMPOUNDS AND METHODS FOR ANALYSIS AND SYNTHESIS OF SACCHARIDE COMPOUNDS | ACADEMIA SINICA (TW) | 2015-06-18 | — | — | US | claimed |
| CN-114530563-B | Organic light emitting device, display device, electronic apparatus, in-vehicle display, and vehicle | 上海天马微电子有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-114276304-B | A process for preparing 1, 5-benzodiazepine derivatives as pharmaceutical intermediates containing fused rings | 南京苏亦欣医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114068834-B | Organic light emitting device, display device, electronic apparatus, vehicle-mounted display screen, and vehicle | 武汉天马微电子有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117050020-A | Synthesis method of pyridazine | 温州大学新材料与产业技术研究院 | 2023-11-14 | — | — | CN | disclosed |
| CN-114890952-B | Preparation method of 5-halogeno-2-aminobenzoazacyclic compound | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-115135697-A | Process for producing polythioether compound | 株式会社大赛璐 | 2022-09-30 | — | — | CN | disclosed |
| CN-114530563-A | Organic light emitting device, display device, electronic apparatus, in-vehicle display, and vehicle | 上海天马微电子有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-114479734-A | Insulating adhesive film, preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2022-05-13 | — | — | CN | disclosed |
| US-20060073472-A1 | Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death | UNIVERSITE DE STRASBOURG (FR) | 2006-04-06 | — | — | US | disclosed |
| CN-1628109-A | Novel aryl-and heteroaryl-piperazines | NOVO NORDISK AS (DK) | 2005-06-15 | — | — | CN | disclosed |
| EP-1430033-A4 | ANTI-INFLAMMATORY AND PROTEIN KINASE INHIBITOR COMPOSITION AND METHOD OF USE | UNIV NORTHWESTERN (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1430033-A1 | ANTI-INFLAMMATORY AND PROTEIN KINASE INHIBITOR COMPOSITION AND METHOD OF USE | NORTHWESTERN UNIVERSITY (US) | 2004-06-23 | — | — | EP | disclosed |
| US-20030176437-A1 | Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2003-09-18 | — | — | US | disclosed |
| WO-2003018563-A1 | ANTI-INFLAMMATORY AND PROTEIN KINASE INHIBITOR COMPOSITION AND METHOD OF USE | NORTHWESTERN UNIVERSITY (US) | 2003-03-06 | — | — | WO | disclosed |
| EP-0650480-B1 | 1-ARYLSULPHONYL-3-PHENYL-1,4,5,6-TETRAHYDROPYRIDAZINES | ORTHO PHARMA CORP (US) | 2001-11-21 | — | — | EP | disclosed |
| US-5684151-A | PROGESTIN AGONISTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| WO-1994001412-A1 | 1-ARYLSULPHONYL, ARYLCARBONYL AND 1-ARYLPHOSPHONYL-3-PHENYL-1,4,5,6-TETRAHYDROPYRIDAZINES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060073472-A1 | Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death | CASP2, CASP1, DAPK2 | L3MBTL1 1685/4885EP300 709/4885HDAC4 1068/4885 |
| US-20030176437-A1 | Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death | CASP2, CASP1, DAPK2 | L3MBTL1 1685/4885EP300 709/4885HDAC4 1068/4885 |
| US-20150168415-A1 | COMPOUNDS AND METHODS FOR ANALYSIS AND SYNTHESIS OF SACCHARIDE COMPOUNDS | MPI, GPI, FUT6 | L3MBTL1 3003/4885EP300 4112/4885HDAC4 967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.