Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.53 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23036946 | 1.00 | MTOR (0.56) | MTORRPTORMLST8GRM5SMN1; SMN2 | |
| SCHEMBL27905732 | 0.78 | ELOVL1 (0.39) | MTORRPTORMLST8 | |
| SCHEMBL1907360 | 0.77 | MAPT (0.63) | MTORRPTORMLST8GRM5SMN1; SMN2 | |
| SCHEMBL38651177 | 0.77 | MAPT (0.63) | MTORRPTORMLST8GRM5SMN1; SMN2 | |
| SCHEMBL1060286 | 0.74 | P2RX7 (0.56) | SMN1; SMN2GAANPC1ATMMAPT | |
| SCHEMBL13933622 | 0.73 | HCAR2 (0.41) | MTORRPTORMLST8 | |
| SCHEMBL15520187 | 0.73 | GRIA1 (0.40) | MTORRPTORMLST8GRIA1 | |
| SCHEMBL29563483 | 0.73 | MPO (0.46) | MTORRPTORMLST8GRM5SMN1; SMN2 | |
| SCHEMBL2643353 | 0.73 | GRM5 (0.46) | MTORRPTORMLST8GRM5SMN1; SMN2 | |
| SCHEMBL2160327 | 0.73 | MPO (0.46) | MTORRPTORMLST8GRM5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112368279-B | Novel compounds as mTOR inhibitors and uses thereof | 医药生命融合研究团 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023250157-A9 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2023250157-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2023-12-28 | — | — | WO | disclosed |