Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | LIPE | Q05469 | 11/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL906222 | 1.00 | LMNA (0.63) | LMNAMAPTNPSR1RAB9ATHRB | |
| SCHEMBL11351938 | 0.91 | MAPT (0.69) | LMNAMAPTNPSR1RAB9ATHRB | |
| SCHEMBL10388794 | 0.87 | LMNA (0.50) | LMNAMAPTNPSR1RAB9ATHRB | |
| SCHEMBL5646066 | 0.84 | MAPT (0.58) | LMNAMAPTNPSR1RAB9ATHRB | |
| SCHEMBL11383589 | 0.83 | LIPE (0.65) | LMNAMAPTNPSR1RAB9ATHRB | |
| SCHEMBL9272113 | 0.83 | THRB (0.76) | LMNAMAPTNPSR1RAB9ATHRB | |
| SCHEMBL8576331 | 0.83 | MAPT (0.65) | LMNAMAPTNPSR1RAB9ATHRB | |
| SCHEMBL21652204 | 0.83 | RAB9A (0.67) | LMNAMAPTNPSR1RAB9ATHRB | |
| SCHEMBL11391846 | 0.83 | LIPE (0.67) | LMNAMAPTNPSR1RAB9ATHRB | |
| SCHEMBL4728325 | 0.83 | KDM4E (0.62) | LMNAMAPTNPSR1RAB9ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362221-A | Synthesis method of stable-killing essence | 傅廷国 | 2024-01-09 | — | — | CN | disclosed |