SCHEMBL8576331

SCHEMBL8576331

[O]c1ccc(Oc2ccc(C(F)(F)F)cn2)cc1

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
LMNA P02545 1/20 0.63
RAB9A P51151 1/20 0.59
THRB P10828 1/20 0.58
LIPE Q05469 12/20 0.58
BCHE P06276 1/20 0.56
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11351938 0.91 MAPT (0.69) MAPTNPSR1LMNARAB9ATHRB
SCHEMBL10387449 0.83 LMNA (0.68) MAPTNPSR1LMNARAB9ATHRB
SCHEMBL21652204 0.83 RAB9A (0.67) MAPTNPSR1LMNARAB9ATHRB
SCHEMBL4728325 0.83 KDM4E (0.62) MAPTNPSR1LMNARAB9ATHRB
SCHEMBL906222 0.83 LMNA (0.63) MAPTNPSR1LMNARAB9ATHRB
SCHEMBL30690168 0.83 LMNA (0.63) MAPTNPSR1LMNARAB9ATHRB
SCHEMBL11383589 0.83 LIPE (0.65) MAPTNPSR1LMNARAB9ATHRB
SCHEMBL9272113 0.83 THRB (0.76) MAPTNPSR1LMNARAB9ATHRB
SCHEMBL11391846 0.83 LIPE (0.67) MAPTNPSR1LMNARAB9ATHRB
SCHEMBL9507549 0.83 MAPK1 (0.64) MAPTNPSR1LMNARAB9ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55092369-A None JP disclosed
US-5756425-A Fluazifop-butyl formulation and process for the selective control of Bermuda and other grasses in Bentgrass and St. Augustinegrass turf ASH DAVID (US) 1998-05-26 US disclosed
EP-0191282-A1 1-Aryl-4-nitropyrazoles BAYER AG (DE) 1986-08-20 EP disclosed
EP-0084819-A2 Herbicidal agents containing methabenzthiazuron in combination with certain phenoxypropionic acid esters BAYER AG (DE) 1983-08-03 EP disclosed
EP-0056807-A4 CERTAIN 2-(4-((5-TRIFLUOROMETHYL)-2-PYRIDINYL)OXY)PHENOXY)-N-PYRIDINYL PROPANAMIDE AND DERIVATIVES THEREOF AND A METHOD FOR SELECTIVELY CONTROLLING GRASSY WEEDS IN RICE. DOW CHEMICAL CO (US) 1982-12-09 EP disclosed
EP-0061112-A1 Compounds and method for selectively controlling grassy weeds in broadleaved crops THE DOW CHEMICAL COMPANY (US) 1982-09-29 EP disclosed
EP-0056807-A1 CERTAIN 2-(4-((5-TRIFLUOROMETHYL)-2-PYRIDINYL)OXY)PHENOXY)-N-PYRIDINYL PROPANAMIDE AND DERIVATIVES THEREOF AND A METHOD FOR SELECTIVELY CONTROLLING GRASSY WEEDS IN RICE THE DOW CHEMICAL COMPANY (US) 1982-08-04 EP disclosed
US-4330321-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1982-05-18 US disclosed
WO-1982000401-A1 CERTAIN 2-(4-((5-TRIFLUOROMETHYL)-2-PYRIDINYL)OXY)PHENOXY)-N-PYRIDINYL PROPANAMIDE AND DERIVATIVES THEREOF AND A METHOD FOR SELECTIVELY CONTROLLING GRASSY WEEDS IN RICE TOBOL H 1982-02-18 WO disclosed
WO-1982000400-A1 METHOD FOR SELECTIVELY CONTROLLING GRASSY WEEDS IN RICE SMITH L 1982-02-18 WO disclosed
JP-S5592369-A PREPARATION OF 4-(5-TRIFLUOROMETHYLPYRIDIN-2-YLOXY) PHENOXY ALKANOIC CARBOXYLIC ACID OR ITS DERIVATIVE ISHIHARA SANGYO KAISHA LTD 1980-07-12 JP disclosed