SCHEMBL906222

SCHEMBL906222

Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.63
MAPT P10636 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
RAB9A P51151 1/20 0.59
THRB P10828 1/20 0.58
LIPE Q05469 11/20 0.58
BCHE P06276 1/20 0.56
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.51
SCN9A Q15858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30690168 1.00 LMNA (0.63) LMNAMAPTNPSR1RAB9ATHRB
SCHEMBL11351938 0.91 MAPT (0.69) LMNAMAPTNPSR1RAB9ATHRB
SCHEMBL10388794 0.87 LMNA (0.50) LMNAMAPTNPSR1RAB9ATHRB
SCHEMBL5646066 0.84 MAPT (0.58) LMNAMAPTNPSR1RAB9ATHRB
SCHEMBL11383589 0.83 LIPE (0.65) LMNAMAPTNPSR1RAB9ATHRB
SCHEMBL9272113 0.83 THRB (0.76) LMNAMAPTNPSR1RAB9ATHRB
SCHEMBL8576331 0.83 MAPT (0.65) LMNAMAPTNPSR1RAB9ATHRB
SCHEMBL21652204 0.83 RAB9A (0.67) LMNAMAPTNPSR1RAB9ATHRB
SCHEMBL11391846 0.83 LIPE (0.67) LMNAMAPTNPSR1RAB9ATHRB
SCHEMBL4728325 0.83 KDM4E (0.62) LMNAMAPTNPSR1RAB9ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0028870-B1 PHENOXYPYRIDINE COMPOUND IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-16 EP claimed
EP-0003877-B1 HERBICIDAL DERIVATIVES OF 2-(4(2-PYRIDYLOXY)PHENOXY)PROPANE, PROCESSES FOR PREPARING THEM, AND HERBICIDAL COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-02-03 EP claimed
EP-0058173-B1 PROCESS FOR THE SYNTHESIS OF ARYLOXY DERIVATIVES ICI AUSTRALIA LIMITED (AU) 1984-12-05 EP claimed
EP-0017767-B1 TRIFLUOROMETHYL PYRIDINYL(OXY/THIO)PHENOLS THE DOW CHEMICAL COMPANY (US) 1983-03-02 EP claimed
EP-0057473-A2 A process for preparing trifluoromethylpyridyl (oxy/thio) phenoxypropionic compounds being especially active as herbicides THE DOW CHEMICAL COMPANY (US) 1982-08-11 EP claimed
EP-0028870-A1 Phenoxypyridine compound IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-05-20 EP claimed
EP-0017767-A1 Trifluoromethyl pyridinyl(oxy/thio)phenols THE DOW CHEMICAL COMPANY (US) 1980-10-29 EP claimed
US-4152328-A 2-PHENOXY-5-TRIFLUOROMETHYLPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF ISHIHARA SANGYO KAISHA LTD. (JP) 1979-05-01 US claimed
JP-54061182-A None JP disclosed
JP-55092369-A None JP disclosed
JP-58210080-A None JP disclosed
CN-117510338-A Natural naphthoquinone derivative and preparation method and application thereof 贵州大学 2024-02-06 CN disclosed
CN-117362221-A Synthesis method of stable-killing essence 傅廷国 2024-01-09 CN disclosed
CN-116217470-A Aryloxy-phenoxy compound and application thereof as herbicide 沈阳中化农药化工研发有限公司 2023-06-06 CN disclosed
EP-0003890-A2 Herbicidal pyridine compounds and herbicidal compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-09-05 EP disclosed
JP-S5461182-A 2-PHENOXY-5-TRIFLUOROMETHYLPYRIDINE COMPOUNDS ISHIHARA SANGYO KAISHA LTD 1979-05-17 JP disclosed
US-4152328-A 2-PHENOXY-5-TRIFLUOROMETHYLPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF ISHIHARA SANGYO KAISHA LTD. (JP) 1979-05-01 US disclosed
EP-0001473-A2 Herbicidal halogenomethyl--pyridyloxy-phenoxy-alkanecarboxylic acids and derivatives, and processes of controlling unwanted plants therewith IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-04-18 EP disclosed
WO-1979000094-A1 HERBICIDAL PYRIDINE COMPOUNDS ICI LTD (GB) 1979-03-08 WO disclosed
EP-0000483-A1 Trifluoromethyl pyridinyl(oxy/thio)phenoxy propanoic acids and propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1979-02-07 EP disclosed