Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30697508 | 0.79 | TDP1 (0.31) | P2RX4NSD2 | |
| SCHEMBL30697478 | 0.79 | LMNA (0.35) | P2RX4NSD2 | |
| SCHEMBL4990398 | 0.69 | LMNA (0.36) | P2RX4 | |
| SCHEMBL4987548 | 0.65 | MAPT (0.42) | — | |
| SCHEMBL5484265 | 0.64 | LMNA (0.42) | P2RX4NSD2 | |
| SCHEMBL4982776 | 0.60 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL3541130 | 0.60 | LMNA (0.34) | P2RX4 | |
| SCHEMBL4992631 | 0.60 | PARK7 (0.35) | P2RX4 | |
| SCHEMBL7393727 | 0.60 | ALDH1A1 (0.47) | — | |
| SCHEMBL4996133 | 0.60 | MEN1 (0.35) | P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002393-A1 | SUBSTITUTED BENZO[f][l ,2,4JTRIAZOL0[4,3-a][l ,4JDIAZEPINES AS GABA A GAMMA! POSITIVE ALLOSTERIC MODULATORS | HOFFMANN-LA ROCHE INC. (US) | 2024-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002393-A1 | SUBSTITUTED BENZO[f][l ,2,4JTRIAZOL0[4,3-a][l ,4JDIAZEPINES AS GABA A GAMMA! POSITIVE ALLOSTERIC MODULATORS | GABRA4, GABRB1, GABRB3 | P2RX4 326/4885NSD2 1152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.