Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.31 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700501 | 0.77 | GRM5 (0.39) | HSD11B1 | |
| SCHEMBL21730877 | 0.74 | MGLL (0.52) | — | |
| SCHEMBL32664208 | 0.74 | MGLL (0.52) | — | |
| SCHEMBL25252026 | 0.72 | HDAC8 (0.31) | — | |
| SCHEMBL30700478 | 0.70 | HSD11B1 (0.38) | HSD11B1USP30 | |
| SCHEMBL30700024 | 0.69 | CA12 (0.39) | HSD11B1USP30 | |
| SCHEMBL27291239 | 0.69 | MGLL (0.41) | — | |
| SCHEMBL30700456 | 0.69 | APLNR (0.39) | HSD11B1USP30 | |
| SCHEMBL30700701 | 0.68 | RAB9A (0.35) | HSD11B1USP30 | |
| SCHEMBL30700264 | 0.68 | MGLL (0.43) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |