Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.37 |
| ▸ | ATXN2 | Q99700 | 6/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 4/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700278 | 0.88 | MGLL (0.46) | F2RMGLL | |
| SCHEMBL30700764 | 0.88 | MGLL (0.46) | F2RMGLL | |
| SCHEMBL30699959 | 0.85 | ENPP2 (0.39) | EPHX2ENPP2ATXN2MGLLALOX5AP | |
| SCHEMBL30700033 | 0.77 | TACR1 (0.38) | P2RX7EPHX2ENPP2ATXN2F2R | |
| SCHEMBL25324356 | 0.76 | ENPP2 (0.42) | P2RX7ENPP2ATXN2TACR1 | |
| SCHEMBL30700290 | 0.75 | MGLL (0.62) | MGLL | |
| SCHEMBL30700736 | 0.75 | HCRTR2 (0.35) | — | |
| SCHEMBL30700147 | 0.74 | MGLL (0.46) | ENPP2ATXN2MGLL | |
| SCHEMBL30700009 | 0.74 | MGLL (0.46) | ENPP2ATXN2MGLL | |
| SCHEMBL30700176 | 0.74 | MGLL (0.46) | ENPP2ATXN2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |