Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MAPK7 | Q13164 | 7/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699959 | 0.88 | ENPP2 (0.39) | HTR2BMAPK7 | |
| SCHEMBL31308055 | 0.81 | ENPP2 (0.37) | HCRTR2GPR119DDR1 | |
| SCHEMBL30700064 | 0.80 | EPHX2 (0.40) | GPR119SCN9A | |
| SCHEMBL30700335 | 0.79 | MGLL (0.44) | PRKAA2 | |
| SCHEMBL30700338 | 0.77 | GPR119 (0.41) | GPR119 | |
| SCHEMBL30700707 | 0.76 | GPR119 (0.40) | GPR119SCN9A | |
| SCHEMBL27290308 | 0.75 | MGLL (0.43) | — | |
| SCHEMBL30700152 | 0.75 | MGLL (0.43) | — | |
| SCHEMBL30700699 | 0.75 | P2RX7 (0.38) | — | |
| SCHEMBL30700417 | 0.75 | MGLL (0.44) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |