Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20028039 | 0.88 | GABRA2 (0.52) | F9F10PLAUGABRA2GABRB2 | |
| SCHEMBL30452306 | 0.88 | ALDH1A1 (0.47) | F9F10PLAUGABRA2GABRB2 | |
| SCHEMBL22309899 | 0.86 | GABRA2 (0.54) | MAPK1NPSR1F9F10PLAU | |
| SCHEMBL22309820 | 0.85 | PDE4D (0.51) | NPSR1GABRA2GABRB2TP53 | |
| SCHEMBL4701544 | 0.83 | ALDH1A1 (0.57) | TBXAS1F9F10PLAUGABRA2 | |
| SCHEMBL29192833 | 0.79 | RAB9A (0.44) | NPSR1F9F10PLAUGABRA2 | |
| SCHEMBL30554010 | 0.77 | SMN1; SMN2 (0.46) | CDC7DBF4ALDH1A1KMT2ATP53 | |
| SCHEMBL27297862 | 0.77 | PDE4B (0.44) | MAPK1GABRA2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL29077940 | 0.76 | GABRA2 (0.49) | TBXAS1MAPK1NPSR1F9F10 | |
| SCHEMBL31325667 | 0.76 | LMNA (0.42) | NPSR1F9F10PLAUALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936496-B | Heterocyclic compounds useful as medicaments | 马萨里克大学 | 2023-12-29 | — | — | CN | disclosed |