Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.47 |
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30722965 | 0.88 | P2RX7 (0.44) | CTSKCTSLCTSBCTSSLMNA | |
| SCHEMBL22225460 | 0.88 | CTSK (0.61) | CTSKCTSLCTSBCTSSATM | |
| SCHEMBL30722986 | 0.85 | CTSK (0.51) | CTSKCTSLCTSBCTSSATM | |
| SCHEMBL9293312 | 0.83 | CTSK (0.48) | CTSKCTSLCTSBCTSSATM | |
| SCHEMBL29365807 | 0.82 | CTSK (0.50) | CTSKATMCYP3A4TSHRCYP2C9 | |
| SCHEMBL30722961 | 0.81 | ALDH1A1 (0.52) | CTSKCTSLCTSBCTSSTSHR | |
| SCHEMBL30722960 | 0.81 | ALDH1A1 (0.52) | CTSKCTSLCTSBCTSSTSHR | |
| SCHEMBL30764688 | 0.79 | CTSK (0.59) | CTSKCTSLCTSBCTSSCYP3A4 | |
| SCHEMBL7469120 | 0.79 | CTSK (0.59) | CTSKCTSLCTSBCTSSCYP3A4 | |
| SCHEMBL3947244 | 0.78 | LMNA (0.51) | CYP3A4TSHRCYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4541791-A1 | DIHYDROOXADIAZINONE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 2025-04-23 | — | — | EP | disclosed |
| CN-119365445-A | Dihydrooxadiazinon compounds and pharmaceutical uses thereof | 日本烟草产业株式会社 | 2025-01-24 | — | — | CN | disclosed |
| US-20240101572-A1 | DIHYDROOXADIAZINONE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2024-03-28 | — | — | US | disclosed |
| WO-2023243686-A1 | DIHYDROOXADIAZINONE COMPOUND AND PHARMACEUTICAL USE THEREOF | 日本たばこ産業株式会社 | 2023-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101572-A1 | DIHYDROOXADIAZINONE COMPOUND AND PHARMACEUTICAL USE THEREOF | PLD2, PLD1, PLD4 | CTSK 422/4885CTSL 983/4885CTSB 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.