Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723336 | 0.90 | HRH3 (0.37) | ALDH1A1PLA2G1BNPSR1ATG4BBCHE | |
| SCHEMBL30723314 | 0.85 | ACHE (0.54) | ALDH1A1PLA2G1BNPSR1ATG4BBCHE | |
| SCHEMBL30723324 | 0.84 | KDM4E (0.38) | ALDH1A1PLA2G1BNPSR1ATG4BBCHE | |
| SCHEMBL30723298 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1BCHEACHEMEN1KMT2A | |
| SCHEMBL30723308 | 0.78 | GAA (0.39) | ALDH1A1BCHEACHEHRH3MEN1 | |
| SCHEMBL30723305 | 0.78 | MAPT (0.40) | ALDH1A1BCHEACHEHRH3MEN1 | |
| SCHEMBL30723299 | 0.78 | ATM (0.46) | ALDH1A1BCHEACHEMEN1KMT2A | |
| SCHEMBL29152982 | 0.78 | HSD17B10 (0.45) | ALDH1A1PLA2G1BATG4BBCHEACHE | |
| SCHEMBL30723307 | 0.78 | TRPV4 (0.44) | ALDH1A1PLA2G1BNPSR1ATG4BBCHE | |
| SCHEMBL30723329 | 0.78 | ALDH1A1 (0.45) | ALDH1A1NPSR1BCHEACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |