Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174582 | 1.00 | KMT2A (0.44) | KMT2AMEN1MAPTALDH1A1TSHR | |
| SCHEMBL30725455 | 0.77 | MAPT (0.50) | KMT2AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL29174604 | 0.77 | MAPT (0.50) | KMT2AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL30725525 | 0.75 | ALDH1A1 (0.38) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL29174594 | 0.75 | ALDH1A1 (0.38) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL30886775 | 0.70 | CA12 (0.51) | KMT2AMEN1MAPTALDH1A1TSHR | |
| SCHEMBL16655014 | 0.70 | CA12 (0.51) | KMT2AMEN1MAPTALDH1A1TSHR | |
| SCHEMBL16654851 | 0.70 | HTR6 (0.53) | MAPK1HTTNOD1 | |
| SCHEMBL31006834 | 0.69 | CCNB2 (0.42) | KMT2AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL29174697 | 0.69 | PKM (0.44) | ALDH1A1ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |