Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23956107 | 0.76 | ALDH1A1 (0.56) | HTR2AHTR2CALDH1A1CYP1A2POLB | |
| SCHEMBL6472453 | 0.76 | SMN1; SMN2 (0.45) | ALDH1A1CYP1A2KDM4EHTTVCP | |
| SCHEMBL5746059 | 0.73 | HTR1B (0.45) | HTR2AHTR2CALDH1A1CYP1A2POLB | |
| SCHEMBL30193576 | 0.67 | KMT2A (0.50) | ALDH1A1KDM4EHTT | |
| SCHEMBL4912683 | 0.67 | KMT2A (0.50) | ALDH1A1KDM4EHTT | |
| SCHEMBL5770349 | 0.64 | HTR1B (0.49) | HTR2AHTR2CALDH1A1CYP1A2POLB | |
| SCHEMBL27903386 | 0.64 | LMNA (0.44) | HTR2AHTR2CALDH1A1CYP1A2POLB | |
| Dimethylamine SCHEMBL11499079 | 0.63 | KMT2A (0.46) | ALDH1A1KDM4E | |
| SCHEMBL28165013 | 0.63 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRHTTLMNA | |
| SCHEMBL8043623 | 0.63 | CCR2 (0.54) | ALDH1A1CYP1A2POLBKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988124-B | Inhibitor of renal glutaminase allosteric site containing oxygen group element diazole or tetrazole structure | 杭州健昵福生物科技有限公司 | 2024-01-09 | — | — | CN | disclosed |