SCHEMBL3073593

SCHEMBL3073593

CCN(O)COc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.45
LMNA P02545 2/20 0.44
TAAR1 Q96RJ0 1/20 0.43
ALDH1A1 P00352 1/20 0.43
RECQL P46063 1/20 0.43
KCNA3 P22001 1/20 0.43
ALOX15 P16050 2/20 0.42
CHRNB2 P17787 2/20 0.41
CHRNB4 P30926 2/20 0.41
CHRNA3 P32297 2/20 0.41
CHRNA7 P36544 2/20 0.41
CHRNA4 P43681 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 1/20 0.41
POLB P06746 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL4244721 0.91 LMNA (0.41) LTA4HLMNARECQLALOX15NPC1
SCHEMBL6002603 0.78 LTA4H (0.49) LTA4HLMNATAAR1KCNA3CHRNB2
SCHEMBL863049 0.73 TAAR1 (0.50) LTA4HLMNATAAR1ALDH1A1RECQL
SCHEMBL12456886 0.73 LTA4H (0.53) LTA4HLMNATAAR1ALDH1A1RECQL
Phenetole SCHEMBL28364557 0.72 LTA4H (0.77) LTA4HLMNAALDH1A1RECQLKCNA3
Phenetole SCHEMBL28109380 0.72 LTA4H (0.77) LTA4HLMNAALDH1A1KCNA3CHRNB2
Hydrochloric Acid SCHEMBL10702571 0.71 ELANE (0.45) ALDH1A1NPC1RAB9ATSHRL3MBTL1
Phenetole SCHEMBL27928571 0.70 LTA4H (0.74) LTA4HLMNAALDH1A1RECQLKCNA3
SCHEMBL45032 0.70 TAAR1 (0.52) LTA4HLMNATAAR1ALDH1A1RECQL
SCHEMBL45031 0.70 TAAR1 (0.46) LTA4HLMNATAAR1ALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467026-B1 HAIR DYEING COMPOSITION AND ITS USE GOLDWELL AKTIENGESELLSCHAFT (DE) 1993-03-03 EP claimed
EP-3906275-A1 BRANCHED ORGANOSILICON COMPOUND, METHOD OF PREPARING SAME, AND COMPOSITIONS COMPRISING SAME Dow Silicones Corporation (US) 2021-11-10 EP disclosed
WO-2020142442-A1 BRANCHED ORGANOSILICON COMPOUND, METHOD OF PREPARING SAME, AND COMPOSITIONS COMPRISING SAME DOW SILICONES CORPORATION (US) 2020-07-09 WO disclosed
WO-2019063611-A1 OXIDATION DYEING PROCESS USING A COUPLER AND A PEROXYGENATED SALT AS OXIDIZING AGENT L'OREAL (FR) 2019-04-04 WO disclosed
CN-108082752-A Aerosol-type cosmetic hair composition 朋友株式会社 2018-05-29 CN disclosed
EP-2760425-A2 FOAM OXIDATIVE HAIR COLORANT COMPOSITION WITH THE FREE-BASE OF 1, 4-DIAMINO-2-METHOXMETHYL BENZENE The Procter and Gamble Company (US) 2014-08-06 EP disclosed
US-8529637-B2 Foam oxidative hair colorant composition with the free-base of 1,4-diamino-2-methoxymethyl benzene THE PROCTER & GAMBLE COMPANY (US) 2013-09-10 US disclosed
US-8523956-B2 Colouring composition for keratin fibres KAO GERMANY GMBH (DE) 2013-09-03 US disclosed
WO-2013049575-A2 FOAM OXIDATIVE HAIR COLORANT COMPOSITION WITH THE FREE-BASE OF 1, 4-DIAMINO-2-METHOXMETHYL BENZENE THE PROCTER & GAMBLE COMPANY (US) 2013-04-04 WO disclosed
US-20130081647-A1 Foam Oxidative Hair Colorant Composition with the Free-Base of 1,4-Diamino-2-Methoxymethyl Benzene THE PROCTER & GAMBLE COMPANY (US) 2013-04-04 US disclosed
US-20130000056-A1 COLOURING COMPOSITION FOR KERATIN FIBRES KAO GERMANY GMBH (DE) 2013-01-03 US disclosed
US-8292972-B2 Foam oxidative hair colorant composition THE PROCTER & GAMBLE COMPANY (US) 2012-10-23 US disclosed
US-20120141398-A1 HAIR DYE CONTAINING ONE OR MORE EDIBLE OR COSMETIC COLORS CHUANG KUO SHENG (TW) 2012-06-07 US disclosed
US-7815692-B1 Hair coloring compositions Universal Beauty Products, Inc. (US) 2010-10-19 US disclosed
US-7419510-B2 High aqueous oxidation haircolor system COMBE INCORPORATED (US) 2008-09-02 US disclosed
US-20060037153-A1 High aqueous oxidation haircolor system COMBE INCORPORTED 2006-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130081647-A1 Foam Oxidative Hair Colorant Composition with the Free-Base of 1,4-Diamino-2-Methoxymethyl Benzene DHODH, AOC1, GPX4 LTA4H 2214/4885LMNA 3173/4885TAAR1 455/4885
US-20130000056-A1 COLOURING COMPOSITION FOR KERATIN FIBRES KRT18, MDN1, CUTA LTA4H 3585/4885LMNA 951/4885TAAR1 1624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.