Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | STAMBP | O95630 | 1/20 | 0.43 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30737363 | 0.90 | HPGDS (0.51) | HPGDSPLK1PSMD14STAMBPCOPS5 | |
| SCHEMBL30737479 | 0.89 | HPGDS (0.53) | HPGDSPLK1PSMD14STAMBPCOPS5 | |
| SCHEMBL30737390 | 0.82 | PLK1 (0.44) | HPGDSPLK1LMNAOPRM1OPRD1 | |
| SCHEMBL30737317 | 0.80 | F10 (0.52) | MEN1KMT2AMAPTOPRM1OPRD1 | |
| SCHEMBL30737175 | 0.78 | SORT1 (0.64) | HPGDSOPRM1OPRD1 | |
| SCHEMBL23474091 | 0.75 | MAPK1 (0.45) | HPGDSPSMD14LMNAMEN1KMT2A | |
| SCHEMBL4257164 | 0.72 | NNMT (0.50) | LMNAMEN1KMT2ARGS12MAPT | |
| SCHEMBL30737283 | 0.71 | PLK1 (0.45) | HPGDSPLK1LMNAMAPTOPRM1 | |
| SCHEMBL30737273 | 0.70 | PLK1 (0.47) | HPGDSPLK1LMNAMEN1KMT2A | |
| SCHEMBL19205985 | 0.70 | ALDH1A1 (0.53) | HPGDSLMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543858-A1 | BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES | Draupnir Bio ApS (DK) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247754-A1 | BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES | DRAUPNIR BIO APS (DK) | 2023-12-28 | — | — | WO | disclosed |