SCHEMBL30737347

SCHEMBL30737347

C#CCOCCOCCOCC(=O)N1CCC(Oc2cccc(Oc3ccc(C(=O)OC)cn3)c2)CC1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRKAA2 P54646 1/20 0.42
MAPT P10636 2/20 0.39
NAMPT P43490 1/20 0.39
KMT2A Q03164 4/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
TNKS O95271 1/20 0.37
PARP1 P09874 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37
HRH3 Q9Y5N1 6/20 0.36
POLB P06746 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737281 0.92 HRH3 (0.36) PRKAA2KMT2ANPC1RAB9AHRH3
SCHEMBL30737188 0.85 SORT1 (0.47) PRKAA2MAPTNAMPTKMT2ATNKS
SCHEMBL30737508 0.81 MAPT (0.43) MAPTKMT2ARAB9AHRH3L3MBTL1
SCHEMBL30737459 0.80 KDM4E (0.44) KMT2AHRH3POLB
SCHEMBL30737266 0.79 SORT1 (0.37) PRKAA2MAPTNAMPTKMT2ANPC1
SCHEMBL30737189 0.79 GPR119 (0.49) PRKAA2
SCHEMBL30737301 0.78 HRH3 (0.38) MAPTKMT2AHRH3
SCHEMBL30737180 0.77 SORT1 (0.46) PRKAA2MAPTNAMPTKMT2ATNKS
SCHEMBL30737405 0.74 PRKAA2 (0.42) PRKAA2KMT2AHRH3L3MBTL1KCNH2
SCHEMBL30737352 0.72 LMNA (0.44) PRKAA2KMT2AHRH3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133234-A1 SORTILIN BINDERS AND BIFUNCTIONAL COMPOUNDS THEREOF DRAUPNIR BIO APS (DK) 2025-06-26 WO disclosed
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed