Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 6/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | MYLK | Q15746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616781 | 0.93 | WDR5 (0.57) | WDR5MEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL30737482 | 0.82 | MEN1 (0.65) | MEN1KMT2AHTR6ALDH1A1POLB | |
| SCHEMBL28271817 | 0.82 | MEN1 (0.65) | MEN1KMT2AHTR6ALDH1A1POLB | |
| SCHEMBL9616547 | 0.82 | WDR5 (0.80) | WDR5MEN1KMT2AALDH1A1RXFP1 | |
| SCHEMBL28513733 | 0.80 | MEN1 (0.66) | MEN1KMT2AHTR6ALDH1A1POLB | |
| SCHEMBL28506242 | 0.80 | MEN1 (0.79) | MEN1KMT2AHTR6ALDH1A1HSD17B10 | |
| SCHEMBL9616784 | 0.78 | HTR6 (0.54) | WDR5MEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL28513321 | 0.78 | MEN1 (0.59) | WDR5MEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL28270335 | 0.76 | HTR6 (0.66) | MEN1KMT2AHTR6POLBKDM4E | |
| SCHEMBL28530757 | 0.76 | HTR6 (0.61) | MEN1KMT2AHTR6ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462179-A4 | NOVEL SULFONAMIDES AS RADIOSENSITIZERS | — | 1992-03-18 | — | — | EP | claimed |
| EP-0462179-A1 | NOVEL SULFONAMIDES AS RADIOSENSITIZERS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-27 | — | — | EP | claimed |
| WO-1990009787-A1 | NOVEL SULFONAMIDES AS RADIOSENSITIZERS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1990-09-07 | — | — | WO | claimed |