Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826265 | 0.85 | CACNB4 (0.49) | MRGPRX4 | |
| SCHEMBL30745366 | 0.83 | MRGPRX4 (0.49) | MRGPRX4ALDH1A1TSHRHTTLMNA | |
| SCHEMBL30740814 | 0.82 | GPR119 (0.42) | — | |
| SCHEMBL30740852 | 0.81 | HSD11B1 (0.41) | ALDH1A1TSHRLMNAMEN1MAPT | |
| SCHEMBL24793341 | 0.77 | MRGPRX4 (0.48) | MRGPRX4ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL27168908 | 0.77 | MRGPRX4 (0.48) | MRGPRX4ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL30745379 | 0.77 | MRGPRX4 (0.47) | MRGPRX4ALDH1A1TSHRHTTLMNA | |
| SCHEMBL30740732 | 0.76 | MRGPRX4 (0.45) | MRGPRX4ALDH1A1TSHRLMNAEPHA2 | |
| SCHEMBL30740829 | 0.76 | LMNA (0.46) | ALDH1A1LMNAMEN1KMT2AEPHA2 | |
| SCHEMBL30745367 | 0.76 | ALDH1A1 (0.49) | MRGPRX4ALDH1A1TSHRHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |