Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.54 |
| ▸ | FGB | P02675 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PLEC | Q15149 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19198126 | 0.83 | LMNA (0.66) | LMNAPRMT1MEN1KMT2AMAPT | |
| SCHEMBL3078521 | 0.83 | USP30 (0.49) | PTPN1MEN1KMT2AMAPTPSMD14 | |
| SCHEMBL3093412 | 0.83 | PRMT1 (0.52) | LMNAPRMT1MEN1KMT2AMAPT | |
| SCHEMBL7674372 | 0.81 | LMNA (0.63) | LMNAPTPN1PRMT1MEN1KMT2A | |
| SCHEMBL3079861 | 0.77 | LMNA (0.49) | LMNAPTPN1PRMT1MEN1KMT2A | |
| SCHEMBL28393150 | 0.77 | ATM (0.50) | LMNAMEN1KMT2AMAPTCYP2C19 | |
| SCHEMBL7670734 | 0.76 | LMNA (0.56) | LMNAPRMT1MEN1KMT2AMAPT | |
| SCHEMBL18085798 | 0.75 | PTPN1 (1.00) | PTPN1PRMT1MEN1KMT2AMAPT | |
| SCHEMBL14534186 | 0.74 | MMP1 (0.71) | LMNAPTPN1PRMT1MEN1KMT2A | |
| SCHEMBL3071850 | 0.73 | KIF11 (0.50) | CA1CA2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234378-A1 | ALKYLSULFONAMIDE-SUBSTITUTED TRIAZOLES AS MATRIX METALLOPROTEASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-09-16 | — | — | US | disclosed |
| WO-2008024784-A1 | ALKYLSULFONAMIDE-SUBSTITUTED TRIAZOLES AS MATRIX METALLOPROTEASE INHIBITORS | ARRAY BIOPHARMA, INC. (US) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234378-A1 | ALKYLSULFONAMIDE-SUBSTITUTED TRIAZOLES AS MATRIX METALLOPROTEASE INHIBITORS | MMP3, MMP11, MMP13 | LMNA 1757/4885PTPN1 2926/4885PRMT1 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.