Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 9/20 | 0.74 |
| ▸ | RAB9A | P51151 | 9/20 | 0.74 |
| ▸ | NPC1 | O15118 | 7/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | TP53 | P04637 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | MAOA | P21397 | 4/20 | 0.67 |
| ▸ | MAOB | P27338 | 4/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | BCL2 | P10415 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801204 | 1.00 | XDH (0.75) | XDHMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL571576 | 0.88 | XDH (0.84) | XDHMAPTRAB9ANPC1ALDH1A1 | |
| Isoformonentin SCHEMBL73338 | 0.86 | XDH (1.00) | XDHMAPTRAB9ANPC1ALDH1A1 | |
| Isoformonentin SCHEMBL30105310 | 0.86 | XDH (1.00) | XDHMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL762092 | 0.85 | MAPT (1.00) | XDHMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL5814089 | 0.84 | XDH (0.78) | XDHMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL13774686 | 0.83 | XDH (0.76) | XDHMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL22340136 | 0.83 | XDH (0.76) | XDHMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL12289033 | 0.83 | XDH (0.76) | XDHMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL2069145 | 0.82 | RAB9A (0.80) | XDHMAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |