Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 13/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620763 | 0.90 | PDE10A (0.52) | ALOX15PDE10ATSHRKDM4E | |
| SCHEMBL9379799 | 0.86 | PKM (0.50) | ALOX15KDM4E | |
| SCHEMBL19579748 | 0.84 | ALOX15 (0.49) | ALOX15PDE10AP2RY12TSHR | |
| SCHEMBL30744775 | 0.83 | RBP4 (0.46) | ALOX15 | |
| SCHEMBL31389285 | 0.83 | ALOX15 (0.70) | ALOX15P2RY12KDM4E | |
| SCHEMBL18528819 | 0.83 | ALOX15 (0.70) | ALOX15P2RY12KDM4E | |
| SCHEMBL19579751 | 0.83 | ALOX15 (0.55) | ALOX15TSHRKDM4E | |
| SCHEMBL4620316 | 0.79 | PLA2G2A (0.47) | PDE10AP2RY12TSHRKDM4E | |
| SCHEMBL5088569 | 0.78 | DHODH (0.45) | ALOX15PDE10AKDM4E | |
| SCHEMBL20515862 | 0.77 | TSHR (0.48) | ALOX15TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |