Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 8/20 | 0.46 |
| ▸ | TTR | P02766 | 7/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5092018 | 0.85 | XDH (0.47) | RBP4TTRXDH | |
| SCHEMBL20515876 | 0.84 | ALOX15 (0.61) | RBP4TTRKMOALOX15XDH | |
| SCHEMBL30438176 | 0.84 | ALOX15 (0.61) | RBP4TTRKMOALOX15XDH | |
| SCHEMBL30744772 | 0.83 | ALOX15 (0.49) | ALOX15 | |
| SCHEMBL9379799 | 0.83 | PKM (0.50) | ALOX15 | |
| SCHEMBL5703892 | 0.78 | RBP4 (0.41) | RBP4TTRKDM5AKDM4CXDH | |
| SCHEMBL5097600 | 0.74 | ALOX15 (0.42) | RBP4TTRALOX15 | |
| SCHEMBL4620763 | 0.74 | PDE10A (0.52) | ALOX15 | |
| SCHEMBL30744837 | 0.73 | ALOX15 (0.57) | RBP4TTRALOX15 | |
| SCHEMBL4620342 | 0.73 | ALOX15 (0.43) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |