Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826647 | 0.86 | GPR119 (0.47) | MEN1KMT2AGAAIDO1 | |
| SCHEMBL30740794 | 0.85 | ALDH1A1 (0.40) | LMNAALDH1A1MEN1KMT2AEPHA2 | |
| SCHEMBL30740733 | 0.85 | ALDH1A1 (0.41) | LMNAALDH1A1MEN1KMT2AEPHA2 | |
| SCHEMBL30740746 | 0.83 | ALDH1A1 (0.40) | LMNAPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL30740755 | 0.81 | LNPEP (0.38) | LMNAALDH1A1OPRK1 | |
| SCHEMBL30740827 | 0.80 | GPR119 (0.38) | — | |
| SCHEMBL30745378 | 0.77 | SCN9A (0.39) | ALDH1A1 | |
| SCHEMBL29826215 | 0.77 | CYP2C9 (0.44) | — | |
| SCHEMBL18497751 | 0.75 | IDO1 (0.56) | IDO1 | |
| SCHEMBL30745372 | 0.75 | LNPEP (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |