Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15866083 | 0.80 | FUCA1 (0.45) | HSD11B1FUCA1SIGMAR1OPRK1OPRL1 | |
| SCHEMBL31172293 | 0.80 | FUCA1 (0.45) | HSD11B1FUCA1SIGMAR1OPRK1OPRL1 | |
| SCHEMBL30748878 | 0.80 | GAA (0.39) | HSD11B1FUCA1SIGMAR1TSHR | |
| SCHEMBL16080213 | 0.80 | ACHE (0.45) | FUCA1SIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL19214942 | 0.75 | CTSL (0.47) | SIGMAR1OPRL1 | |
| SCHEMBL31171606 | 0.75 | MAPT (0.39) | FUCA1OPRK1TSHR | |
| SCHEMBL21748529 | 0.74 | ACHE (0.39) | SIGMAR1CYP3A4HSD17B10OPRL1ALDH1A1 | |
| SCHEMBL21886855 | 0.72 | MEN1 (0.46) | FUCA1SIGMAR1TSHR | |
| SCHEMBL1558447 | 0.71 | SIGMAR1 (0.39) | SIGMAR1HSD17B10ALDH1A1TSHR | |
| SCHEMBL31172333 | 0.70 | RBP4 (0.40) | CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220747-A2 | FLUORINATED CYCLIC DERIVATIVES OF SULFONAMIDES AND SULFONES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2024-10-24 | — | — | WO | disclosed |