Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31496873 | 0.96 | ALDH1A1 (0.32) | LMNAALDH1A1HSD17B10MAOAMAOB | |
| SCHEMBL31496920 | 0.87 | KMT2A (0.32) | SCN9ASCN5AKMT2AHCRTR1HCRTR2 | |
| SCHEMBL31496960 | 0.82 | HCRTR1 (0.32) | ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL31496913 | 0.81 | MAOA (0.35) | ALDH1A1MAOAMAOBSCN9ASCN5A | |
| SCHEMBL31496937 | 0.77 | OPRK1 (0.33) | MAOAMAOBKMT2AHCRTR1HCRTR2 | |
| SCHEMBL31496829 | 0.73 | PARP10 (0.36) | — | |
| SCHEMBL31496961 | 0.70 | FFAR4 (0.31) | — | |
| SCHEMBL30753090 | 0.69 | THRA (0.32) | KMT2A | |
| SCHEMBL31496862 | 0.68 | KCNH2 (0.34) | — | |
| SCHEMBL30752860 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |