Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31496970 | 0.96 | LMNA (0.31) | ALDH1A1LMNAHSD17B10HCRTR1HCRTR2 | |
| SCHEMBL31496960 | 0.86 | HCRTR1 (0.32) | ALDH1A1HCRTR1HCRTR2TSHRHTT | |
| SCHEMBL31496920 | 0.82 | KMT2A (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL31496937 | 0.81 | OPRK1 (0.33) | HCRTR1HCRTR2MAOAMAOB | |
| SCHEMBL31496913 | 0.78 | MAOA (0.35) | ALDH1A1HCRTR1HCRTR2NPC1MAOA | |
| SCHEMBL30753090 | 0.72 | THRA (0.32) | — | |
| SCHEMBL31496862 | 0.72 | KCNH2 (0.34) | — | |
| SCHEMBL31496916 | 0.69 | — | — | |
| SCHEMBL30752860 | 0.68 | — | — | |
| SCHEMBL31496829 | 0.68 | PARP10 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |