Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NQO1 | P15559 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5346628 | 0.85 | ALDH1A1 (0.68) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL15842615 | 0.81 | AHR (0.55) | CA12CA9CA1ALDH1A1NQO1 | |
| SCHEMBL5341818 | 0.81 | KDM4E (0.72) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL9035535 | 0.80 | PIM1 (0.47) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL27903491 | 0.79 | NQO1 (0.58) | CA12CA9CA1ALDH1A1KDM4E | |
| SCHEMBL23640303 | 0.78 | ALDH1A1 (0.50) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL17861315 | 0.78 | ALDH1A1 (0.60) | CA12CA9CA1ALDH1A1KDM4E | |
| SCHEMBL2490464 | 0.78 | PIM1 (0.64) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL2761544 | 0.78 | PIM1 (1.00) | PIM1CA12CA9CA1ALDH1A1 | |
| SCHEMBL2492142 | 0.78 | PIM1 (0.64) | PIM1CA12CA9CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119529133-B | Bifunctional chitosan derivative and preparation and application thereof | 中国科学院烟台海岸带研究所 | 2025-06-17 | — | — | CN | claimed |
| CN-119529133-A | Bifunctional chitosan derivative and preparation and application thereof | 中国科学院烟台海岸带研究所 | 2025-02-28 | — | — | CN | claimed |
| CN-115594772-B | Coumarin starch derivative and preparation and application thereof | 中国科学院烟台海岸带研究所 | 2023-02-21 | — | — | CN | claimed |
| CN-115594772-A | Coumarin starch derivative and preparation and application thereof | 中国科学院烟台海岸带研究所（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-114426587-A | Modified cassia seed polysaccharide and preparation method and application thereof | 河北科技大学 | 2022-05-03 | — | — | CN | claimed |
| CN-112517060-B | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2022-03-25 | — | — | CN | claimed |
| CN-110386998-B | Coumarin inulin derivative and preparation and application thereof | 中国科学院烟台海岸带研究所 | 2021-08-06 | — | — | CN | claimed |
| CN-112517060-A | Catalyst, application and synthesis method of 4-hydroxycoumarin derivative | 山东农业大学 | 2021-03-19 | — | — | CN | claimed |
| CN-108598533-B | Coumarin-based photocyclization crosslinking sulfonated polyimide proton exchange membrane and preparation method thereof | 同济大学 | 2020-11-03 | — | — | CN | claimed |
| US-10730885-B1 | Coumarin derivatives | KING SAUD UNIVERSITY (SA) | 2020-08-04 | — | — | US | claimed |
| CN-110386998-A | A kind of Coumarins synanthrin derivative and its preparation and application | 中国科学院烟台海岸带研究所 | 2019-10-29 | — | — | CN | claimed |
| CN-102846598-A | Application of coumarin in preparing formation inhibitors of advanced glycation end products (AGEs) | GUANGZHOU KANGCHENG PHARMACEUTICAL RES CO LTD | 2013-01-02 | — | — | CN | claimed |
| US-4496727-A | ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | claimed |
| CN-119529133-B | Bifunctional chitosan derivative and preparation and application thereof | 中国科学院烟台海岸带研究所 | 2025-06-17 | — | — | CN | disclosed |
| CN-119529133-A | Bifunctional chitosan derivative and preparation and application thereof | 中国科学院烟台海岸带研究所 | 2025-02-28 | — | — | CN | disclosed |
| CN-119192119-A | Coumarin thioether pleuromutilin derivative and application thereof | 西华大学 | 2024-12-27 | — | — | CN | disclosed |
| US-3993670-A | OPTICAL BRIGHTENERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
| US-3974289-A | Coumarin derivatives for the treatment of allergies | BEECHAM GROUP LIMITED (EN) | 1976-08-10 | — | — | US | disclosed |
| US-3971731-A | OPTICAL BRIGHTENER, UV ABSORBER | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
| US-3968119-A | OPTICAL BRIGHTENERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730885-B1 | Coumarin derivatives | CBR3, KCNH1, CBR1 | PIM1 1060/4885CA12 1474/4885CA9 1053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.